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What about life expansion that meddles with a person’s perception of time? Take someone convicted of a heinous crime, like the torture and murder of a child. Would it be unethical to tinker with the brain so that this person experiences a 1,000-year jail sentence in his or her mind?

Roache: There are a number of psychoactive drugs that distort people’s sense of time, so you could imagine developing a pill or a liquid that made someone feel like they were serving a 1,000-year sentence. Of course, there is a widely held view that any amount of tinkering with a person’s brain is unacceptably invasive. But you might not need to interfere with the brain directly. There is a long history of using the prison environment itself to affect prisoners’ subjective experience. During the Spanish Civil War [in the 1930s] there was actually a prison where modern art was used to make the environment aesthetically unpleasant. Also, prison cells themselves have been designed to make them more claustrophobic, and some prison beds are specifically made to be uncomfortable.