Install the "Python for windows extensions" here:
http://sourceforge.net/projects/pywin32/[
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And for example invoking excel will be possible:
import win32com.client
import pythoncom
xlApp = win32com.client.Dispatch("Excel.Application")
xlApp.Visible=1
workBook = xlApp.Workbooks.Open(r"C:\MyTest.xls")
print str(workBook.ActiveSheet.Cells(i,1))
workBook.ActiveSheet.Cells(1, 1).Value = "hello"
workBook.Close(SaveChanges=0)
xlApp.Quit()
Here a link for invoking ADO:
http://www.ecp.cc/pyado.html[
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Good luck!