WPF

Dim d As DependencyObject        
d = VisualTreeHelper.GetParent( _                
lstItems.ItemContainerGenerator.ContainerFromIndex(0))

static class HelpUtility
{
  static HelpUtility()
  {
    CommandManager.RegisterClassCommandBinding(typeof(FrameworkElement),
      new CommandBinding(ApplicationCommands.Help,
            new ExecutedRoutedEventHandler(Executed),
            new CanExecuteRoutedEventHandler(CanExecute))
        );
  }
  public static string GetHelpKey(DependencyObject dObj)
  {
    return dObj.GetValue(HelpKeyProperty).ToString();
  }
  public static void SetHelpKey(DependencyObject dObj, string value)
  {
    dObj.SetValue(HelpKeyProperty, value);
  }
  public static readonly DependencyProperty HelpKeyProperty =
     DependencyProperty.RegisterAttached("HelpKey", 
     typeof(string), typeof(HelpUtility));

  private static void CanExecute(object sender, CanExecuteRoutedEventArgs e)
  {
    FrameworkElement fe = sender as FrameworkElement;
    if (fe != null)
    {
      if (HelpUtility.GetHelpKey(fe) != null)
        e.CanExecute = true;
    }
  }
  private static void Executed(object sender, ExecutedRoutedEventArgs e)
  {
    System.Windows.Forms.Help.ShowHelp(null, @"HelpFile.chm", 
      System.Windows.Forms.Help.HelpNavigator.Index); // Show the index...
  }
}

<... standard window definitions here, but the next bit is the charm
  xmlns:help="clr-namespace:...mynamespace...">
<Grid>
  <Grid.ColumnDefinitions>
    <ColumnDefinition Width="auto" />
    <ColumnDefinition Width="*" />
  </Grid.ColumnDefinitions>
  <Grid.RowDefintions>
    <RowDefinition />
  </Grid.RowDefintions>
    <TextBox Grid.Column="0" Grid.Row="0" Name="NameField" help:HelpKey="MyName" />
</Grid>
</Window>

<Window x:Class="TestWPFHelp.Window1"
    xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
    xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
    xmlns:help="clr-namespace:TestWPFHelp"
    Title="Window1" Height="300" Width="300">
    <Grid>
        <Grid.ColumnDefinitions>
            <ColumnDefinition Width="auto" />
            <ColumnDefinition Width="*" />
        </Grid.ColumnDefinitions>
        <Grid.RowDefinitions>
            <RowDefinition></RowDefinition>
        </Grid.RowDefinitions>
        <TextBox Grid.Column="1" Height="23" Margin="78,72,80,0" Name="NameFiled" VerticalAlignment="Top" help:HelpKey="MyName" />
    </Grid>
</Window>

ColorBrush.Color.FromArgb(_color.ToArgb());