Its really simple just add event which you can directly select for designer or in code just write following in constructor
textBox1.KeyPress += new KeyPressEventHandler(textBox1_KeyPress);
private void textBox1_KeyPress(object sender, KeyPressEventArgs e)
{
if (char.IsDigit(e.KeyChar) || char.IsControl(e.KeyChar))
{
e.Handled = true;
}
else
{
e.Handled = false;
}
}