If this is something you'll do only once, consider using EXCEL string functions to generate 'INSERT' statements.
Eg:
A | B | C | D
FOO | BAR | BAZ |
12 | 15 | Beer | "INSERT INTO MY_TABLE(FOO, BAR, BAZ) VALUES (" + A2 + ", " + B2 + ", '" + C2 + "');"
999 | 4 | Winw | "INSERT INTO MY_TABLE(FOO, BAR, BAZ) VALUES (" + A3 + ", " + B3 + ", '" + C3 + "');"
If you need to programatically read an EXCEL file using C#, see
this link. Then you can connect to MYSQL and generate insert commands from your C# code.
Hope this helps,
Pablo.