Making Forms Work on Different Screen Resolutions Programatically...

You can use AutoScaleMode property

Before .NET I solved this problem "by hand". I arranged the controls to look ok at the lowest acceptable resolution. Then for higher resolutions I had extra space in the X and Y directions.

I allowed selected controls to "grow" by a percentage of this extra space. For example, my button controls ignored extra space, but a list box would use it to show more of its information to the user.

I also defined rows and columns of controls that would keep the same space between them even when one or more of those controls grew.

With docking and anchoring you can often come up with a simpler solution in .NET.