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to fetch the data from the databse using the selected value from the drop-down list index value
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If you want to use javascript, then you would have to use ajax for this.
 
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This is not a question. Trying to understand it as a question, it's still not sensible. We don't know your DB schema, even if we wanted to do all the work based on this vague phrase. Try doing it yourself, and ask specific questions if you need to.
 
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Just set Autopostback to true on the drop down list and you can handle it all in the code behind. As you are not all that experienced in asp.net I would say this is the easiest way for you to solve your problem. Once you have a better understanding of what you are doing, I would suggest doing it with ajax like Tech Code Freak suggests.
 
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