So, two issues. First is DRY, and the second is that the .delegate() method is deprecated.
Move the logic into a function. Call that logic on page load and on column changes (or when you call the save() method).
function sumOfColumn(){
var total = 0;
$('.Total').each(function () {
var text = this.innerHTML;
var value = parseFloat(text);
if (!isNaN(value)) { total += value; }
});
$('.total_amount').html(total.toFixed(2));
}
$('.Total').change(function(){sumOfColumn();});
$document.ready(function(){sumOfColumn();});