Disable DataGrid Template Column

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C#

WPF

I have Three column in datagrid out of which 2 are templated column with checkbox

<wpf:DataGridTextColumn Binding="{Binding Path=Name}"  Header="Name Of Bank" />

                <wpf:DataGridTemplateColumn Width="SizeToHeader" IsReadOnly="True" Header="First Selection">
                    <wpf:DataGridTemplateColumn.CellTemplate>
                        <DataTemplate>
                            <CheckBox IsChecked="{Binding Path=First}"  Checked="OnChecked" Margin="2,0,2,0" HorizontalAlignment="Center" VerticalAlignment="Stretch" />
                        </DataTemplate>
                    </wpf:DataGridTemplateColumn.CellTemplate>

                </wpf:DataGridTemplateColumn>
                <wpf:DataGridTemplateColumn Width="SizeToHeader" Header="Second Selection">
                    <wpf:DataGridTemplateColumn.CellTemplate>
                        <DataTemplate>
                            <CheckBox IsChecked="{Binding Path=Second}" Checked="OnChecked" Margin="2,0,2,0" HorizontalAlignment="Center" VerticalAlignment="Center" />
                        </DataTemplate>
                    </wpf:DataGridTemplateColumn.CellTemplate>

what i want when i select the checkbox then the respective row and column should be disable to allow user to select only one value in each row and column. I got the index of column but i am not able to disable that column using

Datagrid.Columns[1].IsReadOnly = true;

Help?