why Date control not work Panel which is under Update panel

<table width="500px" >
<tr>
<td>
 <asp:UpdatePanel ID="updatepanel3" runat="server">
                                <ContentTemplate>
<asp:Panel runat="server"  ID="Panel1">

    <asp:Button ID="btn1" runat="server"   Text ="show2"/>

    </asp:Panel>
    </ContentTemplate>
    </asp:UpdatePanel>

     <asp:UpdatePanel ID="updatepanel1" runat="server" >
                                <ContentTemplate>
<asp:Panel runat="server"  ID="Panel2">

    <asp:Button ID="btn2" runat="server"  Text ="show3"/>
     <asp:UpdatePanel ID="UpdatePanel10" runat="server" UpdateMode="Conditional">
                                                                                <ContentTemplate>
                                                                                    <asp:TextBox ID="txtDelDate" CssClass="textbox" runat="server" Width="100px"></asp:TextBox>
                                                                                    <cc1:MaskedEditExtender ID="MaskedEditExtender1" runat="server" CultureName="en-GB"
                                                                                        TargetControlID="txtDelDate" Mask="99/99/9999" MaskType="Date" AcceptNegative="None"
                                                                                        ClearTextOnInvalid="true" ErrorTooltipEnabled="true" OnFocusCssClass="MaskedEditFocus"
                                                                                        OnInvalidCssClass="MaskedEditError" MessageValidatorTip="true" DisplayMoney="Left">
                                                                                    </cc1:MaskedEditExtender>
                                                                                    <cc1:MaskedEditValidator ID="MV1" runat="server" ControlExtender="MaskedEditExtender1"
                                                                                        EmptyValueMessage="Please enter Date" InvalidValueMessage="Invalid Date" ControlToValidate="txtDelDate"
                                                                                        ValidationGroup="DtVal" Display="Dynamic" Font-Size="Smaller" TooltipMessage="DD/MM/YYYY"
                                                                                        EmptyValueBlurredText="Invalid Date" InvalidValueBlurredMessage="Invalid Date"
                                                                                        SetFocusOnError="true"></cc1:MaskedEditValidator>
                                                                                </ContentTemplate>
                                                                            </asp:UpdatePanel>
</asp:Panel>
</ContentTemplate>
</asp:UpdatePanel>

<asp:UpdatePanel ID="updatepanel2" runat="server">
                                <ContentTemplate>
<asp:Panel runat="server"  ID="Panel3">
    <asp:Button ID="btn3" runat="server"  Text ="show1"/>
</asp:Panel>
</ContentTemplate>
</asp:UpdatePanel>
</td>
</tr>
</table>