You can use the readline method to read a file one line at a time: see
7. Input and Output — Python 3.7.7 documentation[
^]. So your code should be something like:
descriptiontext = open("descriptiontext", 'r')
with open(textfilename, 'a') as textfile:
for filename in glob.iglob('*.pdf'):
stat = os.stat(filename)
filesize = stat.st_size
description = descriptiontext.readline()
textfile.write(f'File {filename} has size {filesize} bytes : {description}\n')