If you have SP installed on top of that VS2010 installation, you could try switching the
Development Server to use IIS Express as opposed to the built in Cassini server.
Enabling IIS Express support in VS 2010 Sp1 | ASP.NET Blog[
^]
Aside from that, really can't help you as I haven't used 2010 much for the last 5 years. I would recommend that you migrate to a newer version.