Just a guess:
FA 5B 04 00 = 31.12.2020 18:00
F9 5B 04 00 = 31.12.2020 17:00
E1 05 03 00 = 30.06.2011 17:00
21 06 03 00 = 01.07.2011 09:00
^ this look like the month - 1
Need more samples and details, where does it come from ?
Try couples of samples where only 1 thing vary, Day, Month, Year, Hour.