The 'microsoft.ace.oledb.12.0' provider is not registered on the local machine.

string ExcelContentType = "application/vnd.ms-excel";
        string Excel2010ContentType = "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet";
        if (fileuploadExcel.HasFile)
        {
            //Check the Content Type of the file 
            if (fileuploadExcel.PostedFile.ContentType == ExcelContentType || fileuploadExcel.PostedFile.ContentType == Excel2010ContentType)
            {
                try
                {
                    //Save file path 
                    string filename = Path.GetFullPath(fileuploadExcel.PostedFile.FileName);
                    string DirectoryPath = Server.MapPath("UploadExcelFile/");
                    string strFilepPath = DirectoryPath + fileuploadExcel.FileName;
                    Directory.CreateDirectory(DirectoryPath);
                    //Save File as Temp then you can delete it if you want 
                    fileuploadExcel.SaveAs(strFilepPath);

                    //For Office Excel 2010  please take a look to the followng link  http://social.msdn.microsoft.com/Forums/en-US/exceldev/thread/0f03c2de-3ee2-475f-b6a2-f4efb97de302/#ae1e6748-297d-4c6e-8f1e-8108f438e62e 
                    string excelConnectionString = string.Format("Provider=Microsoft.ACE.OLEDB.12.0;Data Source={0};Extended Properties=Excel 12.0 XML", strFilepPath);
                   
                   // Create Connection to Excel Workbook   
                    using (OleDbConnection connection = new OleDbConnection(excelConnectionString))
                    {
                        OleDbCommand command = new OleDbCommand
                                ("Select * FROM [Sheet1$]", connection);

                        connection.Open();

                        // Create DbDataReader to Data Worksheet 
                        using (DbDataReader dr = command.ExecuteReader())
                        {

                            // SQL Server Connection String 
                            string sqlConnectionString = ConfigurationManager.ConnectionStrings["connectionstring"].ConnectionString;

                            // Bulk Copy to SQL Server 
                            using (SqlBulkCopy bulkCopy =
                                       new SqlBulkCopy(sqlConnectionString))
                            {
                                bulkCopy.DestinationTableName = "SendMail_Emailids";
                                bulkCopy.WriteToServer(dr);
                                //Label1.Text = "The data has been exported succefuly from Excel to SQL";
                               // ScriptManager.RegisterStartupScript(Page, GetType(), "script1", "alert('Excel file successfully imported into DB');", true);
                                ClientScript.RegisterStartupScript(this.GetType(), "myalert", "alert('Excel file successfully imported into DB');", true);
                            }
                        }
                    }
                }

                catch (Exception ex)
                {
                    Response.Write(ex.Message);
                }
            }
        }